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This is argued to provide an explanation of why the West Nile disease has spread more quickly in North America than Europe.
A genetic factor also appears to increase susceptibility to West Nile disease. A mutation of the gene CCR5 gives some protection against HIV but leads to more serious complications of WNV infection. Carriers of two mutated copies of CCR5 made up 4 to 4.5% of a sample of West Nile disease sufferers while the incidence of the gene in the general population is only 1%.
Source: Wikipedia > West Nile Virus
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