Keratoacanthoma Topics

• polymerase chain reaction
• human papillomavirus dna
• spontaneous regression
• dna sequences
• keratoacanthomas
• invasive growth
• ultraviolet radiation
• incidence rate
• human papillomavirus
• malignancy
• chain reaction
• lesions
• kas
• variants
• ka
• trauma
• presentation

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Keratoacanthoma, Keratoacanthoma

No human papillomavirus-DNA sequences were detected in lesions by polymerase chain reaction. It is a disease of the elderly (mean age, 64 years) with an annual incidence rate of 104 per 100,000. It is not associated with internal malignancy. There may be a seasonal presentation of keratoacanthoma that suggests that ultraviolet radiation has an acute effect on the development of KA. KAs may develop in sites of previous trauma. Most cases are the crateriform type, which grow rapidly then undergo spontaneous regression. Less than 2% belong to the rare destructive variants with no regression and persistent invasive growth. These are referred to as keratoacanthoma marginatum centrifugum and mutilating keratoacanthomas and can lead to severe defects.

Source: Wikipedia > Keratoacanthoma