Habenula Topics

• terminologia anatomica
• globus pallidus
• afferent fibers
• median raphe
• pars compacta
• vertebrate animals
• ventral tegmental area
• target
• retroflex
• cell mass
• stria
• cell groups
• epithalamus
• midbrain
• neurosci
• matsumoto
• neuron
• primate
• nucleus
• nuclei

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Habenula, Habenula

The habenular nucleus is a set of well conserved structures in all vertebrate animals. Andres et al. 1999 Currently, the Terminologia Anatomica term refers exclusively to this separate cell mass in the caudal and dorsal aspect of the dorsal thalamus (the epithalamus), embedded in the posterior end of the medullary stria from which it receives most of its afferent fibers. By way of the retroflex fasciculus (habenulointerpeduncular tract) it projects to the interpeduncular nucleus and other paramedian cell groups of the midbrain tegmentum.

Matsumoto M, Hikosaka O. (2009). Representation of negative motivational value in the primate lateral habenula. Nat Neurosci. 12(1):77-84. PMID 19043410 Reward information to the lateral habenula comes from the internal part of the globus pallidus. Hong S, Hikosaka O. (2008). The globus pallidus sends reward-related signals to the lateral habenula. Neuron. 60(4):720-9. PMID 19038227 The outputs of the lateral habenula target dopaminergic regions (substantia nigra pars compacta and the ventral tegmental area), serotinergic regions (median raphe and dorsal raphe nuclei), and a cholinergic region (the laterodorsal tegmental nucleus).

Source: Wikipedia > Habenula