Gastric Ulcer, Gastric Ulcer
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The gastric mucosa protects itself from gastric acid with a layer of mucus, the secretion of which is stimulated by certain prostaglandins. NSAIDs block the function of cyclooxygenase 1 ( cox-1 ), which is essential for the production of these prostaglandins. Newer NSAIDs (celecoxib, rofecoxib) only inhibit cox-2 , which is less essential in the gastric mucosa, and roughly halve the risk of NSAID-related gastric ulceration.
Source: Wikipedia > Peptic Ulcer
Related Links
Web Links
- Adult Health Advisor 2009.1: Stomach Ulcer (Gastric Ulcer), Modified June 13, 2009, 12:00 am
- Gastric Ulcer, Modified October 31, 2006, 12:00 am
- Peptic Ulcers including gastric ulcer, duodenal ulcer and esophageal ..., Modified June 29, 2009, 12:00 am
- Stomach Ulcer (Gastric Ulcer) Medications | Drugs.com, Modified July 1, 2009, 12:00 am
- Peptic Ulcer - [Alternative Medicine], Modified April 22, 2009, 12:00 am
- Stomach Ulcer, Modified May 29, 2009, 12:00 am
- Peptic Ulcer Disease - Topic Overview - Health.com, Modified June 29, 2009, 12:00 am
- Peptic Ulcer, Modified June 23, 2009, 12:00 am
- Digestive System: Stomach Ulcer (Gastric Ulcer), Modified June 15, 2009, 12:00 am
News Links
- Sucampo Reports Top-Line Results Of Phase 2 Clinical Trial Of Cobiprostone For Prevention Of NSAID-Induced ..., Published July 2, 2009, 9:09 am
- Pozen seeks FDA approval for ulcer drug, Published June 30, 2009, 9:28 am
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