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Catecholamine, Catecholamine

Norepinephrine and epinephrine, in turn, are derived from further modifications of dopamine. It is important to note that the enzyme dopamine hydroxylase requires copper as a cofactor (not shown) and DOPA decarboxylase requires PLP (not shown).Catecholamine synthesis is inhibited by alpha-Methyltyrosine , by inhibiting tyrosine-3 monooxygenase.

Some drugs, like tolcapone (a central COMT-inhibitor), raise the levels of all the catecholamines.

Source: Wikipedia > Catecholamine





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