Capacitation Topics

• acrosome reaction
• female reproductive tract
• seminal fluid
• epididymis
• tripeptide
• spermatozoa
• adenosine
• fertilization
• sperm
• ejaculation
• vitro
• fpp

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Capacitation, Capacitation

In vivo this step typically occurs after ejaculation, in the female reproductive tract. In vitro , capacitation can occur in sperm that have either undergone ejaculation or have been extracted from the epididymis.

After this capacitation the sperm must undergo activation involving the acrosome reaction.

The tripeptide FPP (fertilization promoting factor) produced by the male is essential for capacitation. It has a synergistic stimulatory effect with adenosine that increases adenyl cyclase activity in the sperm. FPP is found in the seminal fluid, and comes into contact with the spermatozoa upon ejaculation.

Source: Wikipedia > Capacitation